It's an accronym for "That's God Damn Right". It was made famous by two university students in Montreal who had a bunch of fun impersonating accents and started using in on a fairly regular basis until it became such a joke that they got it tatooed on their ankle.
Cowboy 1: You know what ?? Today was an amazin' day, glad we got our shiet done.
Cowboy 2: TGDR !!
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