To lose most of the words in one's vocabulary and / or the ability to form real sentences for a few days following an MDMA binge; the mental equivalent of the physical damage caused by hangovers; the results of a brilliant night out.
"How was Hype last night?"
"Good, man, he was erm, I did the thing.."
"There's no point asking Tom, he's got a serious case of the vocabubads."