anhedoniac

is one who suffers from anhedonia, the inability to derive pleasure from normal pleasurable things in life.

If someone is depressed, or has one of many different chemical imbalances in the brain.

-Comedians, for example, may be prone to having this, as what actually makes them laugh has been used so much, that that part of the brain has "worn off funny".
Funny incidents and stories are enjoyed less and less, as time goes on.
(Try telling a comedian a joke, any joke.)

A chronic masturbator has a dopamine imbalance, rendering him or her an anhedoniac, incapable of enjoying normal life in a non orgasmic state.

A person with multiple lovers/sexual partners in life cannot settle down to marry. The more they sample, the less they are able to settle, as a direct result of wanting something "strange" or "new" all the time.

Beautiful, rich people in Hollywood have, or can have anything, or everything, or almost any ONE they could ever want, anytime and all the time. Anhedonia from repeatedly fulfilling their desires is a forgone conclusion in some cases.

(In old school parlance, "too much of a good thing".)

(This may effect more people than we know as the pursuit of pleasure on this planet for it's own sake is rampant.)
e.g. "I can't WAIT for the weekend!"

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