1. A fictional weapon featured in the movie Mystery Men that, when activated, caused those in the vicinty to turn on one another.
2. An attempt to shift blame for your failures.
Michael Brown broke out the blamethrower to avoid responsibility for FEMA bungling Katrina recovery.
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When your significant other starts griping about everything at you all at once.
S1: Why didn't your do the dishes, or walk the dog? What about laundry? Have you looked for a job?
S2: Easy there with the blamethrower!