To jerk off with such frequency that one develops blisters on their palm, resembling Tenome from Pan's Labryinth.
Jack choked the chicken so often when his girlfriend was out of town he developed blisterbates.
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Masterbating for so long it leaves blisters
" I was at home all weekend by myself. I put on some porn and masterbated so long I got blisters."
"Aw man, blisterbate is the worst. You need to find a girlfriend."