1. When things go in your favor, albeit in a nerdy way.
A reference to a Simpsons episode in which Milhouse first complains about wearing his "dorky highwater shorts" but feels better when the floodwater "soaks his ankles" but leaves his cuffs "bone dry," at which point he exclaims "Alright, everythings coming up Milhouse."
Example: I was picked as the "Best Edward from Twilight Look-alike" at the Springfield Bi-Mon Sci-Fi Con. Looks like everything is coming up Milhouse.
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When all possible choices or venues have been exhausted with no favorable result.
I tried to find the DVD at Wal-Mart, Best Buy, Circuit City, even at the pawn shop, but everything's coming up Milhouse.
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A celebratory phrase used following one, or a series of, positive, though generally insignificant event(s).
Its origin can be attributed to Milhouse, a character of television show The Simpsons, who coined the phrase in jubilation after realising the success of his flood pants to keep his cuffs bone dry.
"I left work 10 minutes early today, and I found $2 in the passenger seat of my car! Everything's coming up Milhouse!"
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Means "Everythings going well for me". Came from the Simpsons character MilHouse when something particulary swell happened to him.
I just found 10 bucks, everything's coming up Milhouse!
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An exclamation added to the end of a sentence... e.g. when you hate flood pants but then you realize how effective they really are.
"My feet are soaked, but my cuffs are bone dry! Everything's coming up Milhouse!"
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Words of joy about something insignificant, especially in comparison to how disastrous your situation is.
My train is 3 hours delayed, but I found a spot to sit on the dirty floor. Everything's coming up milhouse!