a total bitch or someone whos on a whole new level of bitchiness.
guy1: "Fuckin ho just pushed me down a flight of stairs for telling her she should let her hair down!!"
guy2: "What a Cruella De Bitch!!"
To cleanse or be cleansed of any thoughts of women, mainly for a brief stint, and especially after a horrible relationship.
After getting dumped, he decided to de-bitch himself until he felt comfortable dating again.