Devilweed, is a slang word for marijuana. The term originated in Eastern Washington, thus is refered to as a hick, or redneck word for the drug.
Father: Have you been toking on the devilweed?
Son: No I have bad allergies so my eyes are red, honest!
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Hey man you want some Mexican Devilweed?
Heck yeah, I'll go make some salsa.
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