Beat down by the world and it's woes, trials, and tribulations; poor or impoverished; oppressed. Almost always used to describe a person or group of people in a truly sad state of things.
That guy doesn't seem simply out of luck, he seems downtrodden
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A man known to officials only as "Mister E." (pronounced "mis-tuh-ree"), that watches over Baltimore's downtrodden. It is rumored that when he was a younger affluent man, he was jailed after being falsely accused of a crime that would have had him killed had he not been saved by a poor, uneducated, black man in his cell.
Man, you hear that the Defender of the Downtrodden has gotten another brother released from that slammer?
Look, a bird, a plane, the Defender of the Downtrodden.
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