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The medical condition in which one has a freakishly large big toe.
Aaron: Dude, Zack, why can you pick up rocks and stuff with your toes?
Zack: I have gigantoe. It's my blessing and my curse.
the state of having a giant phallus; figuratively, bold as a man with a giant phallus
I couldn't keep denying the Holocaust after facing such poor reception. Ahmedinejad must have a case of giganto phallicism.
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A very very fat person that kids call giganto
Sam is a giganto said Alex he has. Fat ass too