pka

a community on amino where everyone is toxic as fuck !!!

normal fc in a comm: hey
dumbass alias: im pka famous lol who are you??

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pka

PKA, an acronym for Previously Known As, or Professionally Known As.

"The artist was previously known as William York"
"pka William York"

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PKA

Protein Kinase A

G protein-coupled receptor kinases (GRKs) represent a class of proteins that classically phosphorylate agonist-activated G protein-coupled receptors, leading to uncoupling of the receptor from further G protein activation. Recently, we have reported that the heterotrimeric G protein á-subunit, Gáq/11, can mediate insulin-stimulated glucose transport. GRK2 contains a regulator of G protein signaling (RGS) domain with specificity for Gáq/11. Therefore, we postulated that GRK2 could be an inhibitor of the insulin signaling cascade leading to glucose transport in 3T3-L1 adipocytes. In this study, we demonstrate that microinjection of anti-GRK2 antibody or siRNA against GRK2 increased insulin-stimulated insulin-responsive glucose transporter 4 (GLUT4) translocation, while adenovirus-mediated overexpression of wild-type or kinase-deficient GRK2 inhibited insulin-stimulated GLUT4 translocation as well as 2-deoxyglucose uptake. Importantly, a mutant GRK2 lacking the RGS domain was without effect. Taken together, these results indicate that through its RGS domain endogenous GRK2 functions as a negative regulator of insulin-stimulated glucose transport by interfering with Gáq/11 signaling to GLUT4 translocation. Furthermore, inhibitors of GRK2 can lead to enhanced insulin sensitivity.

The PKA for a common brown rat, in fasta format is:
gb|AAQ81631.1|

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PKA

It stands for Pi Kappa Alpha. They are called PIKE's for short.

Their national slogan is "Men who love men to love them."

They tend to gravitate towards being firemen and love to shower together.

PKA? Pi Kappa Alpha?
(Group Shower)

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PKA

A silly podcast consisting of three silly friends such as Woodysgamertag, kyle aka FPS russia, and a high functioning retard known as taylor.

Me: hey bro did you taylor from pka said a mildly funny joke, woody and kyle laughed to make feel part of the show.
Richard: who are you? Get out of my house!

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pka

a cult, based in maple ridge.

"PKA is the coolest cult ever"

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PKA stats

Synthesized information for the purpose of making a point or furthering an argument.

Matt: No way 1 out of 10 cops kills an innocent man every day.
Jordie: Fine, those were just pka stats. They really are evil though.