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When one sticks his own or a partners testicles inside the anus of a person.
They were having such rough sex that he gave her a San Francisco Hole in Two.
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When a gay man gets a huge cock in his ass. As the top man pulls out his dick will leave a hole resembling that of a San Francisco man hole. cock asshole gay
"man i got fucked so hard by Jimmy's fat cock, he gave me a San Francisco man hole! I'm still recovering from Friday night."
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Derogatory nickname for San Jose CA
I have to take the bus from 'sacto down to san hole. Long ride! Butt will be sore!