A chronic disease in which the sufferer often will uncontrollably sketch off. A debilitating stigma follows the sufferer, and they often have trouble keeping friends and getting laid.
John, a long time sufferer of sketcholepsy, has been with a woman only twice. However, both experiences ended in violent sketch offs, in which he disappeared in less than 3 seconds.
His best guess as to what a female breast feels like is a bag of sand, thanks for his favorite movie - The 40 Year Old Virgin.