The Extermination of one or more universes (including parallels & multi-verses)
It is occasionally practiced by scientific geniuses who are artificially-voiced & wheelchair bound.
The tendency is especially pronounced in the progenitors of machine-creatures.
There have been two factually documented attempts - thankfully both were unsuccessfull.
"Detonate the reality bomb! AHAHAHAHAA"
(Davros, attempting verse-icide from the dalek crucible)
"Activate the Large Hadron Collider! AHAHAHAHAAA"
(stephen hawking, attempting verse-icide at CERN)