What someone says when they are caught off-guard and in slight disbelief of a statement; they say "wuzzat?" a shortened form of "what's that?" to express their current state.
Monokuma: "Let's begin with a basic explanation of the class trial! So, your votes will determine the results.
Aoi Asahina: "We already know who did it!"
Monokuma: "Wuzzat...?"
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The disorientation and mental confusion one feels after a particular intense sexual session.
"huh? Um... Sorry, I just have a case of the cum-wuzzats. He was magnificent."