When a persons chest has more zits on it then any other part of his/her body. It can also be used to insult or offend someone.
Vinny: Dude! Check out Mary, shes got zitty titties!
Bendino: Thats nasty!
Carlito: Hey zitty titties, come over here for a second.
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When a female has large amounts of zits on her breasts they are referred to as zitty-titties. Also known as rackne.
Did you see Lisa in her zip down top? The zipper was too low and her zitty-titties were all showing.