A sizeable volume of drugs (particularly marijuana) that someone is is in possession of.
Hit up my dawg Manny. He's got loud.
One who spreads misery and maleficence. An unchivalrous, debased person with no sense of dignity or honor.
Knight 1: "Watch out for that neer-do-well. He has tried to lie to and to cheat us before."
Knight 2:"Is there no rest for a crestfallen malefactor?"