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The worst insult you can call someone. It is typically used when you are really really pissed off at someone.
Wow coach why are you such a fucking once all the time?
South Korean Girl Group TWICE fandom.
ONCE: I just bought KNOCK KNOCK
Thrice: Twice sucks
ONCE: I'll KNOCK KNOCK the **** out of you
Onc means on crip that gang members of the crip organization use while texting
Tyrone: these girls be playing too much
Marquon: that’s onc cuz
A popular Steam community group (One Nut Crew) that initiates their members through shooting one of their testicles with a revolver, typically one made from gold. Officially formed April 24, 2013 by founder Keenan "Vern" Evans, ONC frequents many games, usually online, such as Garry's Mod, RoboCraft, Minecraft, Unturned, ARMA 2/3, and many others. They can be found on the steam community website under OneNutCrew.
"I ran into those ONC guys a while back, I could tell they were doing initiations by the gun shots followed by a long, high pitched scream."
In the same tradition of 'deuce,' a once is going number one in the bathroom. A once is a noun, like a piss.
Hey I'll be right back, I got to go drip a once.