Fairly common term used to describe the process of events that occur when two individuals meet, grow romantically involved and have sex.
Bob and Sheila got together for a date. They hit it off and went back to Sheila's place. One thing led to another and they ended up sleeping together.
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A phrase used by men when telling stories. This phrase is used almost inevitably referring to sex.
We went back to my apartment and started watching the movie. well, one thing led to another and the next thing you know i'm banging her
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An excuse for why you cheated on your girlfriend/boyfriend or wife/husband/partner/significant other...
Most often used my rather sheepish looking men
We were just talking and then one thing lead to another...
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used to describe a variety of nonspecific topics, activities, or duties.
What with one thing and another, she hadn't gotten much sleep lately.
While this is a sexual innuendo, it is often a misunderstood phrase by the naive and used as general cause and efffect.
The pastor suggested two people go out for prayer but when she used the phrase, “one thing led to another” the parties misunderstood and ended up taking things further then intended.
When you cheated on someone but you excuse it as something that "just happened" and you didn't want it to. It rarely works because you're a human being and you can control your actions.
Jake: Babe sorry we were just hanging out, I complemented her makeup, and one thing led to another, I didn't mean it
Mary: Yeah right, we're done Jake!