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When someone talk's too much, or speaks out of turn.
If you RUN YO MOUTH one more time, ya dead.
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When a smart and experienced guy gets a sheltered girl with no experience to go through 1st, 2nd, 3rd, and Home base in one night.
"Dude i got Stacy over to my house for a crazy ass home run night!"
"Dude, she go all the way?"
"Hell Yeah!"
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to jack off
My girlfriend is out of town so i'll have to run the hand truck tonight
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In reference to Call of Duty games, it is a fancy way of saying "Nobody will hear me" when you are sneaking into or out of a house or other building you weren't supposed to leave/enter to begin with.
Buddy: Dude, are you seriously going to come with me later? Won't your parents hear you?
You: Relax, I'm running Ninja up in this biatch.
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usually, meaning comes over or go somewhere.
Hey jay come run through the spot really quick I got to show u something
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When somebody ruins something or when somebody will ruin something because they are not good enough at it.. Whether it is a game, joke or saying. Most commonly used in a basketball game: "Yo don't suss the run with your game."
Yo, stop sussin the run with your jokes.
Don't suss the run with that weak ass shot of yours.
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When you hit someone and run off which leaves them hurt and mad, often making them chase you and tackle you down.
John: i hit someone and ran
Jon: So did I
John: OH! We both did a Hit N' Run!
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