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A young lesbian. Analogous to a gay twink or twinkie, although the girl version is never cream filled. Can be identified by the flat billed hat, multiple tattoos, wife beater and high top sneakers.
Abby: OMG! Is that Justin Bieber over there?! I'm totally gonna go make out with him!
Jessy: No way girl! That boy has boobs...I think it's a twyke!
A female that expresses the traits embodied by a twat and simultaneusly by a dyke, therefore a Twyke.
Bro that girl is such a twat, no wait she's a dyke. No wait she's a Twyke.
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