When your vital organs join in on masturbating.
When you can't spell orgasm for... legal reasons.
When you need a word to combine organism and orgasm for whatever reason, do not ask why.
Steam user 1: Ayo, I just had the best organsm of my life.
Steam user 2: Did you mean orgasm?
Steam user 1: Yes but I am not allowed to say it because Something important depends on
Steam user 2: Ah, ok.
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Reddit post: Idk if you know this but I got so aroused by a bacteria shaped like a penis under a microscope that I had an orgasm after jerking off to it