To have sexual intercourse, specifically penile penetration of a soft tissue orafice. Originated with the internet slang term p33n and worked its way into speech through overuse by internet geeks.
"...I walk in and she's getting peeninated by six guys from the football team!"
A man having vaginal intercourse with a woman. To peen someone is to stick his genitals into hers.
Billy came home to find that another man was peenin his wife.
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