When you're too sick to operate normally but not sick enough to skip school/work. Symptoms include: excessive sneezing, runny nose,sore throat, headache, etc.
"Dude you look terrible"
"Yeah... I feel pretty bad"
"Then go home and get some rest"
"Can't I'm only semi-sick"
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When you have school or work tomorrow, and you feel sick, but you know damn well that it's not sick enough to not go
Mom: you have school tomorrow
Jeff: everything feels wrong
Mom: L bozo
Jeff: welp, guess I have semi-sickness