To break or to be broken down into tiny identical (common) parts. Similar to obliterate, annihilate, etc.
"With a carefully calculated swing of the axe, he esmitherated the beautiful glass vase."
"It is possible to observe the previously esmitherated particles under a microscope."
"Can I esmitherate that, please?"
"Was that achieved by a process of esmitheration?"
"He felt utterly esmitherated."